AGER (advanced glycosylation end product-specific receptor)
نویسندگان
چکیده
منابع مشابه
Association between the Advanced Glycosylation End Product-Specific Receptor Gene and Cardiovascular Death in Older Men
Advanced glycosylation end product-specific receptor (AGER) signaling has been implicated in atherosclerosis. The aim of this study was to evaluate whether a common genetic variation in the AGER gene is associated with cardiovascular (CV) death. We included 1304 older men who were genotyped for rs1035798:C>T, which is a single nucleotide polymorphism (SNP) mapped to the third intron of AGER. Co...
متن کاملNon-specific binding of advanced-glycosylation end-products to macrophages outweighs specific receptor-mediated interactions.
On binding to murine peritoneal macrophages, maleylated BSA exhibited saturable-binding kinetics, with about 24000 sites/cell. Prolonged incubation of BSA with > 20 mM glucose or 2 months incubation with > or = 0.5 M glucose induced the modified protein to readily bind non-specifically to both cell and tube surfaces. Kinetic studies on the binding of advanced glycated end-products (AGEs) and ot...
متن کاملPolymorphisms in the advanced glycosylation end product-specific receptor gene and risk of incident myocardial infarction or ischemic stroke.
BACKGROUND AND PURPOSE Recent findings of an association between polymorphisms of advanced glycosylation end product-specific receptor (AGER) and risk of diabetic vasculopathy have generated great interest. However, to date, no genetic-epidemiological data are available on risk of atherothrombotic events among nondiabetic populations. METHODS Using DNA samples collected at baseline in a prosp...
متن کاملPresent-day key roles in nursing administration.
Present-day nursing administration has many goals, roles and functions. Predominant among the roles are those of: programme planner, manager of material resources, man ager of human resources, educator, clinician and researcher. These and other roles relate to clients, colleagues, the agency, the community and the profession. The roles are not discrete, but overlap and intertwine with each oth...
متن کاملDifferential binding of the HIV-1 envelope to phosphatidylserine receptors
Prior work has shown that the HIV-1 envelope of the human immunodeficiency virus (HIV) interacts directly with T-cell immunoglobulin mucin (TIM) family proteins. Herein, we demonstrate that HIV-1 envelope glycoproteins from varying HIV-1 clades bind differentially to TIM proteins and functionally similar proteins acting as phosphatidylserine (PtdSer) receptors. Using enzyme-linked immunosorbent...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology
سال: 2011
ISSN: 1768-3262
DOI: 10.4267/2042/44975